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Because of its restricted range, few bites have been reported. No statistics are available.
Relatively little is known about the toxicity and composition of the venom. In mice, the intravenous LD50 is 1.1 mg/kg. The venom is supposedly slightly less toxic than those of B. arietans and B. gabonica. The maximum wet venom yield is 200 mg. One study reported that this venom has the highest i.m. LD50 value -- 8.6 mg/kg -- of five different viperid venoms tested (B. arietans, B. gabonica, B. nasicornis, Daboia russelii and Vipera aspis). Another showed that there was little variation in the venom potency of these snakes, whether they were milked once every two days or once every three weeks. In rabbits, the venom is apparently slightly more toxic than that of B. gabonica
There are only a few detailed reports of human envenomation. Massive swelling, which may lead to necrosis, had been described. In 2003 a man in Dayton, Ohio, who was keeping a specimen as a pet, was bitten and subsequently died. There is at least one antivenin that protects specifically against bites from this species: India Antiserum Africa Polyvalent.